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Seborrheic Dermatitis

Etiology

Background                                                                                                                                                                                                   

  • Although the name implies that seborrheic may be eczematous in nature, the term dermatitis here is used loosely, as seborrheic dermatitis often displays overlapping features of eczema and psoriasis.  

Treatment

Isotretinoin                                                                                                                                                                                                     

Isotretinoin is an effective therapy for seborrheic dermatitis:

King A, Tan MG, Kirshen C, Tolkachjov SN. Isotretinoin for the management of moderate-to-severe seborrheic dermatitis: A systematic review. J Am Acad Dermatol. 2023. PMID: 37453557.

MY SUMMARY: Systematic review of isotretinoin for seb derm.  7 studies including 229 patients deemed relevant.  Average dose was ~10mg/d for 4 months.  Overall, performed better than itraconazole, antifungal shampoo, and SA soap.  45% had complete/excellent clearance, and only 4% reported no benefit.  Relapse rate at 3 months was ~11%.  Those with truncal SD seem to get most benefit, followed by face, then scalp.  

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